The paper shares the experience of implementation of STEM-based learning in undergraduate programs, organized through networking collaboration between Siberian Federal University and STEM-Games LLC. Proposed gamification model is applied through the first year of Introduction to Engineering course as a stage of students’ first acquaintance with the problems of engineering profession. STEM-based learning activities are shaped into two modules representing a team-based engineering design competition with emphasis on different aspects of engineering. The modules utilize the principles of CDIO bringing up project-based approach and active learning as primary educational techniques. The paper address major issues concerning seamless intercurricular integration of STEM-based learning. Finally, the paper shares the most recent results of the institutions’ collaboration within CDIO-based programs of SibFU. Significant point is made in students’ abilities for self-study and problem solving. Proposed contextual gaming activities put attention to practical importance of natural sciences, being as a starting point for developing students’ engineering thinking and learning motivation.